Archive | Health

Common bone drugs linked to risk of esophageal cancer

People who take common osteoporosis drugs called biphosphonates for over five years may be increasing their risk to develop esophageal cancer, according to a British study on Friday.

Researchers who took part of the study said that the outcomes were alarming, but should not let doctors to change their practice on biphosphonates abruptly. Biphosphonates were prescribed for used by older people to help strengthen their weak and feeble bones.

Jane Green of Oxford University’s Cancer Epidemiology Unit said that they have to worried with the situation; however, she said that it was the first comprehensive study with continuing follow up that has found the outcome, and it is only an observational analysis. Moreover, the research was available in the British Medical Journal.

In addition, Green said in a telephone interview that because esophageal cancer is not common, an increase in risk is still a low risk.

Biphosphonates are a type of drug made to help bone fractures and equalize weakness of the bones linked with osteoporosis and menopause. They include Warner Chilcott’s Actonel, Novartis’s Reclast, Roche’s Boniva and Merck & Co’s Fosamax.

Also, Green and her associates from Medicines and Healthcare products Regulatory Agency (MHRA) of Britain examined data from the UK General Practice Research file on men and women whose age are beyond 40 and had either colorectal cancer, stomach cancer or esophageal cancer detected between 1995 and 2005.

They have discovered that people having 10 or more prescriptions for biphosphonates, or having prescriptions more than five years, had almost doubled the risk of esophageal cancer, in comparison with people who did not have prescriptions on biphosphonates.

Furthermore, they stated on their study that in North America and Europe, the cases of esophageal cancer at age 60-79 is usually 1 per 1,000 populations more than five years, and this is expected to rise to approximately 2 per 1,000 with five years’ use of oral bisphosphonate.

Posted in Health0 Comments

Critics Emerges With Quetiapine Use for PTSD

Critics loom over the use of the controversial drug Seroquel genetically known as quetiapine used to patients with Post Traumatic Stress Disorder (PTSD) as it caused the death of young veteran.

The controversial death of Andrew White, a 23-year-old Marine corporal, claims tons of queries on whether or not Seroquel is the accurate drug to treat PTSD.

Quetiapine is an atypical antipsychotic drug used to treat schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression, and used off-label for other purposes, including insomnia and anxiety disorders.

Plenty of soldiers experiencing PTSD are treated with Seroquel making it Veteran Affairs Department’s finest treatment expenditures hitting fifth for the top selling drug.

However, some soldiers died while taking the pill leaving family to question if the government reviews drug dispensed for militaries.

Andrew White arrived home from a nine-month tour to Iraq plagued by signs of PTSD.  Doctors prescribed him with the antipsychotic drug, Seroquel.

Doctors prescribed White with higher dosage of the drug after complaining that nightmares persisted… He was given 1,600 milligrams of seroquel a day—double the maximum dose used by patients with schizophrenia. White died in his sleep.

Stan White, a retired high school principal, Andrew’s father stated that the doctor told Andrew that he could take another dose if sleeplessness continues.

Investigations by the Veteran Affairs Department showed that White died because of drug interactions.  White was discovered to be taking antidepressant and an anti-anxiety pill, as well as a painkiller all at the same time in which he had no prescription.

It is, however, unclear if whether or not Seroquel accounts for the death of some soldiers. Seroquel’s side effects diabetes, weight gain and uncontrollable muscle spasms have previously resulted for lawsuits. During the course of treatment, White gained 40 lbs and experienced slurred speech, disorientation and tremors.

Researchers at Vanderbilt University published a study posing for a new risk of the drug, sudden heart failure. The study in the January 2009 edition of the New England Journal of Medicine stated that there were three deaths per year for patients taking antipsychotic drugs like Seroquel.

AstraZeneca PLC, makers of the drug along with FDA now conducts own study. White’s death caused his family to search for explanation and for ways to prevent further deaths.

Posted in Health0 Comments

Race Predicts Blood Clotting Risk for Patients with Stent Implant

US research found out that Black patients are at high risk of having blood clots after an implantation of drug-coated stent than any other patients.

The study concentrated on 7,200 patients who had stent implants from the year 2003 up to 2008.

Researchers found out that the race (black) is the strongest predictor that blood clots are more likely to occur after one month that the stent was put into place.  Researcher added that black among any other risk pose greater risk of developing blood clots.

A stent is an artificial tube inserted to support weakened arteries preventing them from collapse.

The study also takes into consideration other conditions airing greater risk for blood clots.  Results showed that black people are at higher risk of developing blood clots.  This predisposes black people at high risk for high blood pressure and kidney problems researcher also added.

Research shows that occurrence for thrombosis after 30 days was 1.71 percent for black while 0.59 percent for non-blacks.  After 36 months, figures rose 3.67 percent among blacks and 1.25 percent among non-blacks.  Deaths amongst black after 36 months sums up to 24.9 while 13.1 percent in non-black.

Findings held true even though black people were given prescribed higher doses of anti clotting medication compared to other races as stated by the author of the study.

Dr. Ron Waksman, associate director of the cardiology division at Washington Hospital Center and a professor of medicine and cardiology at Georgetown University said in the news release that black people were posed for this blood clotting risk not because their health is compromised but their genes suggest a different thing.

Authors of the study suggest deeper research to genetically analyze black people for the right treatment.

Posted in Health0 Comments

Research Says Potential Overdose for Under Five Getting Oral Meds

Australian Researchers stated that children under five have the potential for accidental overdose by parents who cannot actually give the right dose of medications.

Dr. Rebekah Moles, from the University of Sydney, takes on 97 adults consisting of 53 mothers, seven fathers, and day care staffs. The study, which was presented in Lisbon, revealed that 61% of them measured the wrong dose, 17% measured overdose, and 44% was not able to give enough.

Over the counter medicines, variety of spoons and dosing device were made available during the trial.  Volunteers were given and a scenario and were asked what to do whenever these cases happen.  Overall assessment reveals that only 75% were able to calculate accurately whereas 61% would have given an erroneous dose.

Study reveals 7% of the participants would give medicine though temperature was not yet taken while 46% gives medicine even with 38 degrees fever. Only 14% directed the situation correctly added Moles.

From the 119,000 emergency calls received by the New South Wales Poisons Information Centre half concerns accidental overdose with 15% needing hospitalization stated Moles. Cases involved children aged under five. The researcher presented findings at the International Pharmaceutical Federation in Lisbon.

Moles also added that there are surprisingly number of parents that think over the counter drugs are safe because these drugs are accessible.  Instances include a mother believing that paracetamol can be given double dose.

These findings urge the government to review drugs that readily available for the consumers.

Neal Patel of the Royal Pharmaceutical Society of Great Britain said that in is important that parents are knowledgeable of the correct dose they give their children and should ask doctors if not exactly sure with the dose.

Margaret Peycke, from the National Pharmacy Association stated that household spoon should not be used as substitute as dosing device since they do not yield accurate dosage.

Posted in Health0 Comments

Waxman, Stupak Announce a Hearing on September 14

Henry A. Waxman, the chairman of House and Energy Commerce, and Subcommittee Chairman Bart Stupak announced that the Subcommittee on Oversight and Investigations will conduct a hearing on September 14 with regard to the safety of food supplies.

The hearing will examine the safety of food supplies and it will also provide more information about the salmonella outbreak that is associated with chicken eggs.

The salmonella outbreaks are linked with the companies in Iowa, Hillandale farms and Wright County Egg. The two companies both recalled 550 million eggs this month because of salmonella outbreak. The nationwide salmonella outbreak sickened almost 1,300 people.

The committee asked Orland Bethel, the owner of Hillandale farms, and Austin “Jack” DeCoster, the owner of Wright County Egg, to testify in the hearing that will be conducted by the Subcommittee on Oversight and Investigations. According to reports, DeCoster has a history of animal cruelty and violations with regard to the safety of workers.

Stupak and Waxman sent letters to the Department of Agriculture and Food and Drug Administration (FDA) to ask for some documents and information with regard to the egg recall. The two chairmen also requested documents and information to Wright County Egg and Hillandale Farms of Iowa about the salmonella outbreak and the voluntary egg recall.

According to Rep. Rosa DeLauro, chair of the committee that manages the appropriations of FDA and USDA, he sent a letter to both agencies because they did not take action against DeCoster farms. He said that many workers were forced to handle the manure and dead chickens with their bare hands. He also said that the workers were forced to live in filthy trailers.

DeLauro said that different environmental laws were violated repeatedly by the companies and they also failed to disclose its investments in egg operations.

Posted in Health0 Comments

Rates of British men with esophageal cancer increases

Esophageal cancer rates in British men have increased by 50 percent in Great Britain in a generation, a rise that is likely being pushed in part by continuing rate of poor diet and obesity, according to scientists on Saturday.

Also, researchers with the charity Cancer Research UK said, dubbed as the “fat man of Europe”, Britain is by far have higher rates of a kind of esophageal cancer called adenocarcinoma that is linked to obesity having a diet of high saturated fat.

Moreover, Janusz Jankowski of Barts & The London School of Medicine & Dentistry, whose research was supported by the charity, said that the obesity epidemic may be the main reason following the rise. They also stated that being overweight is also associated with the essential increase in the risk having adenocarcinoma. Adenocarcinoma is the major type of esophageal cancer that is on the increase.

They also said that changes in diets are probably linked with the increase; because people are tending to eat less fruits and vegetables.

Rates if adenocarcinoma in Britain were now among the main concerns in the world, which includes the United States that suggests factors in terms of genetics and rates of obese people can also be linked to the increase, Jankowski said in a telephone interview.

It is expected that Jankowski and his team will publicizes the outcome of the study into the factors of genetics that is likely behind the causes of the disease in six months time.

Also, he said that when the time that it will be published, that is the only time that they can say whether it is nature or nurture.

Furthermore, while in 1983, 9.6 in all 100,000 men in Britain were diagnosed having esophageal cancer, as shown on the figures by the Cancer Research UK. By now it is 14.4, a rise of 50 percent.

Posted in Health0 Comments

Cessation in smoking helps patients with post-serious heart attack

Smokers who quit smoking after having a serious heart attack have a lower chance of recurrent heart attacks and can live longer than those people who continued to smoke following an attack.

However, there are only a few known benefits of quitting among patients undergone heart attack left with a complication called left ventricular (LV) dysfunction. LV dysfunction is damage to the heart wherein there is a significantly reduced rate of blood-pumping efficiency in the heart’s main pumping chamber.

Moreover, Dr. Amil M. Shah, the lead researcher on the new study and a staff cardiologist at Brigham and Women’s Hospital in Boston said that it has been not clear whether the dysfunction could aggregate the heart benefits of quitting smoking.

Nonetheless in their analysis, Shah and his associates revealed that survivors of heart attack having LV dysfunction may help to benefit as much from quitting smoking as other patients suffering from heart attack do.

Among 2,231 patients with LV dysfunction, the researchers discovered that patients who quit smoking in the period of six months of their heart attack were less probable to die within the span of five years or undergo a recurrent heart attack than smokers who persisted to do the habit.

Meanwhile, of all the patients, 463 were already smokers at the time they suffered from heart attack yet quit six months later, and 268 continues to smoke within six months. Among people who have quit smoking, 15 percent of them died or undergone another heart attack by the conclusion of the study, which trailed the patients for up to five years.

In comparison among patients who were still smoking even after their primary onset of heart attack, the rate is 23 percent.

Furthermore, people who stopped smoking were about 30 percent less possibly to die, experience a heart attack or be brought to the hospital because of heart failure throughout the study period.

Posted in Health0 Comments

Protein generated in arthritis appears to protect patients against Alzheimer’s disease

According to U.S. scientists, the protein generated in cases arthritis rheumatoid seems to defend patients against Alzheimer’s disease.

Furthermore, in the Journal of Alzheimer’s Research study, the test given to mice with memory loss appears to be managed better after giving a protein. The artificial version of GM-CSF protein is previously used as a medication for cancer.

On the other hand, according to the experts from UK, the research was an essential initial step and examinations were required to distinguish if the medicine worked for individuals with Alzheimer’s disease.

In addition, in persons with arthritis rheumatoid, the immune system goes into overuse and generates offensive proteins such as GM-CSF. It had previously been acknowledged that individuals with rheumatoid arthritis were less possible to acquire Alzheimer’s disease.

However, the defensive connection had been belief to be expected to non-steroidal anti-inflammatory drugs (NSAIDs) taken by individuals with the condition. Moreover, in this research, the researchers from South Florida University genetically modified mice to have memory troubles same as seen with people who have Alzheimer’s disease in a type of dementia.

The study was run for 20-days and mice with Alzheimer’s disease cured with GM-CSF managed significantly better on examinations calculating learning and memory, and acted at a same standard to mice of the similar age without the condition.

Moreover, even the mice that were healthy cured with GM-CSF acted somewhat healthier than their uncured fellows. On the other hand, mice with Alzheimer’s disease that were given the excuse kept on to do weakly in the experiments.

The researchers have recommended the protein may appeal an invasion of cells also known as microglia from the secondary blood stream around the brain that then hit the trait plaques that form in individuals with Alzheimer’s disease.

Posted in Health0 Comments

North Carolina insurance official to talk on business medical insurance provisions

An official from Association for the Advancement of Retired Persons (AARP) in North Carolina discussed about changes of provisions on what the healthcare bill and the business medical insurance will convey.

Many small businesses owners think how the health care legislation will be able to modify their business medical insurance plans. In addition, the senior citizens are also worried on the health care program such as Medicare.

Bill Wilson, AARP official, said that grants offered under the Medicare program will be carried on under the latest health care legislation and senior citizens may also anticipate that in some cases, the availability of Medicare will go on for the next 10 years.

Also there will also enhancements of wellness and precautionary care coverage for those on Medicare that may strip down the expenses those Medicare members will pay on their own.

However, Mr. Wilson stated that when speaking on how that healthcare legislation will influence employers, companies who have less than 50 employers have no requirements that health care insurance will promoted under the latest legislation.

Moreover, on a positive note, only two percent of all businesses across the country will be under the said increases in their health costs insurance because of changes from the healthcare legislation.

The effects of the latest healthcare legislation and insurance of health options are not exclusively indicated to North Carolina, as people from all over the country have apprehensions on how they will pay costs of medical treatment if they are suddenly hit by an illness or disease and they do not have coverage with regards to healthcare. Many employers offer health insurance for their employees but in some cases, small business owners do not have any health care insurance for their subordinates, which caused officials to review the provisions.

Posted in Health0 Comments

Scientists find eating green leafy vegetables can lower risk of having diabetes

Approximately 180 million people all over the world have diabetes and scientists found that eating more green leafy vegetables can drastically reduce the risk of having it.

Furthermore, British researchers studied six previous researches on the connections between eating of vegetable and fruits and diabetes and found eating additional servings per day of vegetables like broccoli, cabbage and spinach declined the risk of adults of having type II diabetes by 14 percent.

The findings do not show that the vegetables themselves stop type II diabetes which is frequently connected to lack of exercise and weak diet and is getting the levels of pandemic as the rates of obesity increases.

In addition, people who consume more green leafy vegetables may also have an overall healthy diet, financially stable and do exercise more and one of those aspects can influence how possible they are to acquire diabetes.

However, the researchers from Patrice Carter of the Diabetes Research Unit at Leicester University said that the findings imply that green leafy vegetables are important. The findings were reported in the British Medical Journal.

The research was included over 200,000 individuals whose age range between 30 and 74, in Finland, China and in the United States. Furthermore, Carter told in a telephone interview that vegetables and fruits are all good, but the information extensively prove that green leafy vegetables are specifically appealing, so more research is needed.

Moreover, she also said that green leafy vegetables have omega 3, magnesium and fatty acids known as antioxidants, all of which have been revealed to have a healthful benefits. Every researches that Carter and co-workers examined and followed the groups of adult, documenting how much servings of vegetables and fruits each accomplices ate everyday then analyzing who was detected to have type II diabetes.

Posted in Health0 Comments